What is equivalent to tretinoin over the counter?

Tretinoin (the generic form of Retin-A) is a proven effective treatment for acne, aging skin, scarring, and hyperpigmentation.

While it is very popular, tretinoin is not available over-the-counter. If you’d like to try tretinoin, you’ll have to reach out to a healthcare professional to obtain this prescription product.

Why can’t you get tretinoin over-the-counter?

While you can get other helpful skincare acids over-the-counter, these products are not classified as medications.

Like with other prescription medications, patient consultation and evaluation are required for safe usage; prescribed dosages and duration of treatment should be overseen by a medical professional.

Tretinoin is a powerful medication

In the same way, you can buy the anti-inflammatory Advil at the grocery store, you’d have to go to your doctor for prescription-strength anti-inflammatory medications. When it comes to prescription retinoids, these are pharmaceutical-grade treatments.

Retinoid products purchased over-the-counter are cosmetic-grade. The FDA regulates and approves pharmaceutical-grade ingredients, while cosmetic-grade over-the-counter treatments are not evaluated by the FDA.

What about over-the-counter alternatives?

If you want to dip your toes in the retinoid treatment waters without a prescription, there are a few over-the-counter options.  Keep in mind that these treatments are not tretinoin (aka retinoic acid), and do not behave exactly like tretinoin. They are in the same family with varying strengths and effects.

  • Retinol is available over-the-counter

Retinol is a part of the vitamin A family but is considerably weaker than tretinoin. For this product to work, a 2 step oxidative conversion must take place on the skin. This makes retinol very gentle and the effects take much longer (than tretinoin) to become visible.

Learn more:Is Tretinoin The Same As Retinol?

  • Adapalene is available over-the-counter

Commonly known as the brand name Differin, adapalene is available in low concentrations over-the-counter. This treatment is great for those treating acne and have very sensitive skin. (Tretinoin is a great acne treatment, but it can be very irritating to some.)

The retinoid cheat sheet

Where to buy, Retinoid, Uses:

OTC: Retinol - Gentle on the skin but requires a conversation process so benefits up to 6-12 months to become visible.

OTC: Adapalene (Differin) - A comedolytic that helps keep pores clear. Slightly less effective at treating acne than tretinoin but comparable.

Prescription: Retinoic acid topical (tretinoin)(Retin A) - Resurfacing anti-aging treatment great for wrinkles, scars, discoloration, and signs of aging. Also treats acne.

Prescription: Oral isotretinoin (Accutane) - Oral treatment for severe acne.

Now, you can buy tretinoin online

While you can’t buy tretinoin over-the-counter, you can get a tretinoin prescription online. It’s never been easier to try the real thing.

You can consult with a doctor remotely, and if they find you’d benefit from tretinoin, they’ll approve your prescription and some online companies can fill this prescription too.

Strut Health offers compound tretinoin products online

No, tretinoin is not available over-the-counter, but this is the next best thing.

If you’d like to try a prescription-strength retinoid, simply complete our questionnaire-based online doctor's consultation.

Our doctors will review your input and if you’re a good fit, we can prescribe one of our tretinoin-containing formulas and ship it right to you.

We have expertly formulated tretinoin-containing products designed to improve acne, melasma, signs of aging, and acne scars. If you think you’d benefit from a prescription-strength retinoid, we’re here to help make it as easily accessible and cost-effective as possible.

In our extensive search for non-irritating retinols, we've discovered plenty of standouts that are at once ultra-effective yet gentle enough for the retinoid-intolerant. What makes these non-Rx gems so transformative is that they all contain either pure retinol or a next-generation derivative shown to turn on those same aforementioned receptors to spark visible change.

What kind of skin-care products include retinol?

Before we explore their individual merits, heed this brief buyer-beware: There are a ton of serums and oils on the market masquerading as retinols. You won't find retinol (or any recognizable derivative) on their ingredient lists since as they rely on plant extracts, like rosehip oil, as alternate sources of vitamin A. 

"There is no evidence that natural sources of retinoids are safer than synthetic, and often their effectiveness is highly suspect," according to cosmetic chemist Kelly Dobos. For instance, she says that rosehip oil contains only about 0.4 parts per million (0.00004 percent) of retinoic acid, which is further diluted in the final product.

To help you sort the amazing products from their suspicious or just-average counterparts, keep scrolling for 25 of our favorite, dermatologist-approved retinol creams, serums, and treatments.

Sunday Riley 5 Stars Retinoid + Niacinamide Eye Serum

Sunday Riley 5 Stars Retinoid + Niacinamide Eye Serum

If we could give Sunday Riley's 5 Stars Retinoid + Niacinamide Eye Serum a rating, well, I think you know what that would be. Treat your delicate eye area to this lightweight serum doused in retinol ester and liposome-encapsulated retinol to strengthen your skin's natural collagen production, while niacinamide brightens instances of discoloration. 

Rounding out the dream team is a moisturizing blend of ceramides and olive oil to fortify the good 'ol barrier, so your skin retains more moisture over time and doesn't flake, itch, or generally look angry.

RoC Retinol Correxion Eye Cream

RoC Retinol Correxion Eye Cream

For a dependable retinol eye treatment that has withstand the test of time, may we point you in the direction of RoC's Retinol Correxion Eye Cream, a three-time Best of Beauty Award winner. Pure, stabilized retinol helps seriously relax any creases you may have and it's accompanied by an antioxidant-rich complex of zinc, copper, and magnesium, which Mona Gohara, M.D., associate clinical professor at Yale School of Medicine, told us aids in the formation of skin-plumping collagen.

Best Retinol Serums:

Youth to the People Retinal + Niacinamide Youth Serum

Youth to the People Retinal + Niacinamide Youth Serum

Made with retinal, a vitamin A derivative that evens out the skin's texture, the Youth to the People Retinal + Niacinamide Youth Serum is a great "clean" pick in this category. The formula also holds niacinamide to minimize dark spots and adaptogenic mushrooms to smooth and replenish moisture in the skin.

Peace Out Retinol Face Stick

Peace Out Retinol Face Stick

The convenience of the Peace Out Retinol Face Stick is why we love it. Packed into this easy-to-use stick is an effective three-percent blend of encapsulated retinol to soften fine lines, a blend of papaya and pumpkin enzymes to minimize pores, and bakuchiol to even out texture. We suggest taking it on the go with you for touch-ups throughout the day.

RoC's Derm Correxion Fill + Treat Serum 

RoC Derm Correxion Fill + Treat Serum

RoC's Derm Correxion Fill + Treat Serum gets an A+ for convincing us to skip a round of filler or even botox. Its three forms of hyaluronic acid immediately make a noticeable difference to plump up lines, while retinol helps create a smooth base — hence why it earned a 2022 Best of Beauty award.

Farmacy 1% Vitamin A Retinol Serum 

Farmacy 1% Vitamin A Retinol Serum

Farmacy's 1% Vitamin A Retinol Serum is made with a bunch of skin-loving ingredients that will have you seeing results fast. First on the list is retinal, which immediately delivers a tightness to the skin that works to improve texture. Next is retinol, to fight wrinkles and fine lines, and lastly Kalahari melon oil, to soothe and replenish moisture. 

Peter Thomas Roth Even Smoother Glycolic Retinol Resurfacing Serum

Peter Thomas Roth Even Smoother Glycolic Retinol Resurfacing Serum

$65 may seem a bit steep but let us explain why we believe the Peter Thomas Roth Even Smoother Glycolic Retinol Resurfacing Serum is worth every buck. Made with a formula of glycolic acid and retinol, the texture of your skin will become clearer and smoother over time. There's also hydrating and plumping ingredients like hyaluronic acid and collagen, as well as niacinamide so issues like dark spots and discoloration become things of the past.

Alastin Skincare Renewal Retinol .5

Alastin Skincare Renewal Retinol .5

New York City-based board-certified dermatologist Marina Peredo, M.D., tells us that the retinol in Alastin Skincare's Renewal Retinol .5 is encapsulated, which improves stability and allows for slower delivery over time. She adds that "the antioxidants, including hydroxymehtoxyphenyl decanone, supports [the production of] natural hyaluronic acid." 

What is as effective as tretinoin?

Retinol is like the training wheels for tretinoin and other dermatology-grade retinoids. They have similar benefits and can be used on any skin type, though tretinoin is more often recommended to treat acne and is FDA approved for photoaging.

What can I alternate tretinoin with?

Tazarotene. Also prescription only. Tazarotene may well be more effective than tretinoin an adapalene at treating acne and possibly more effective than tretinoin at treating sun related aging. Tazarotene is more stable under UV light than tretinoin and can be used in the morning.

Is tretinoin can be bought over

Tretinoin is a synthetic version of vitamin A. It's stronger, and you need a prescription from your doctor for this medication.

Is tretinoin 0.05% over

However, it does not completely or permanently erase these skin problems or greatly improve more obvious changes in the skin, such as deep wrinkles caused by the sun or the natural aging process. This medicine is available only with your doctor's prescription.