Which of the following is the most common side effect of tissue plasminogen activator (tpa)?
Show
What is alteplase (TPA, Activase, Cathflo Activase)?Alteplase is an injectable drug, given directly into a vein, that is used to treat conditions caused by arterial blood clots including heart attacks, strokes, chest pain at rest (unstable angina), blood clots in the lungs (pulmonary thrombosis or embolus), and other less common conditions involving blood clots. What brand names are available for alteplase?TPA, Activase, and Cathflo Activase are brand names available for alteplase. Is alteplase (TPA, Activase, Cathflo Activase) available as a generic drug?No Do I need a prescription for alteplase (TPA, Activase, Cathflo Activase)?Yes What are the uses for alteplase (TPA, Activase, Cathflo Activase)?
What are the side effects of alteplase (TPA, Activase, Cathflo Activase)?The most common and serious side effect of alteplase is bleeding. Minor bleeding is more common, but significant bleeding such as into the brain (intracranial hemorrhage) or fatal bleeding also occurs. Other important side effects include:
Other possible serious side effects include:
What is the dosage for alteplase (TPA, Activase, Cathflo Activase)?
SLIDESHOWHeart Disease: Causes of a Heart Attack See SlideshowWhich drugs or supplements interact with alteplase (TPA, Activase, Cathflo Activase)?Alteplase breaks down clots and thereby interferes with the body's ability to stop bleeding. Therefore, drugs which also interfere with the body's ability to form blood clots (or the clot-promoting effects of platelets) increase the risk of bleeding in patients receiving alteplase. Such drugs include
Is alteplase (TPA, Activase, Cathflo Activase) safe to use during pregnancy or while breastfeeding?
What else should I know about alteplase (TPA, Activase, Cathflo Activase)?What preparations of alteplase (TPA, Activase, Cathflo Activase) are available?Powder is mixed with sterile water for injection: 2, 50, and 100 mg vials. How should I keep alteplase (TPA, Activase, Cathflo Activase) stored?
How does alteplase (TPA, Activase, Cathflo Activase) work?
When was alteplase (TPA, Activase, Cathflo Activase) approved by the FDA?
IMAGESHeart Illustration Browse through our medical image collection to see illustrations of human anatomy and physiology See ImagesSummaryAlteplase (Activase; Cathflo Activase; TPA) is a drug prescribed to treat conditions caused by arterial blood clots such as heart attacks, strokes, chest pain from unstable angina, and pulmonary embolism. Review side effects, drug interactions, dosage, and pregnancy safety information prior to taking this medication. Multimedia: Slideshows, Images & Quizzes
Related Disease Conditions
Treatment & DiagnosisMedications & SupplementsPrevention & WellnessSubscribe to MedicineNet's Heart Health NewsletterBy clicking "Submit," I agree to the MedicineNet Terms and Conditions and Privacy Policy. I also agree to receive emails from MedicineNet and I understand that I may opt out of MedicineNet subscriptions at any time. Report Problems to the Food and Drug AdministrationYou are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088. References FDA Prescribing Information What is the most common side effect of tPA?Because TPA is a powerful blood thinner, the main side effect is bleeding. Bleeding is a serious complication that can result in a hemorrhagic stroke, which is often more serious than an ischemic stroke.
Does tPA have side effects?Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome): dizziness. fever. nausea, vomiting.
What is the major risk factor with using tPA as thrombolytic therapy?The most feared complication of tissue plasminogen activator (tPA) therapy for acute stroke patients is symptomatic intracerebral hemorrhage (SICH).
Which of the following is the most common adverse event of alteplase?The hematologic side effect, bleeding, is the most common adverse event in all approved indications. The incidence of bleeding among patients with acute myocardial infarction who received alteplase (often with aspirin and heparin) ranged from 8% to 77% (0.5% to 10% serious).
|